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The Atlanta Research & Education Foundation is designed to facilitate collaborations between the Department of Veterans Affairs Medical Center in Atlanta and other institutions. We welcome your interest in our facility, personnel, and research capabilities.

Working with the larger research community, AREF is one of the leading foundations in the country devoted to improving research, education, and ultimately healthcare for our nation's Veteran population.

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Investigator: Shan Yu
Phone: (404) 712-8678
Primary Research Interest: Neurology
Description of Research: My grant supported research is to develop novel treatments of brain injuries. We have demonstrated that our neurotensin receptor 1 agonists can effectively reduce the body and brain temperature and show significant neuroprotective effects in rodent models. We are investigating the optimal conditions and long term effects of the treatment using cellular, bioengineering, molecular and animal behavioral tests. We have also being working on new mechanism of AD pathogenesis.
Relevance to VA: Stroke, traumatic brain injury (TBI) and Alzheimer's Disease (AD) affect many veterans and have been the major threats to veteran's life and health. There are so far very limited treatments for those veteran patients.

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